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Dermal Fillers & Injectables Comparison Chart

You can choose from a wide variety of wrinkle-reducing dermal fillers (such as Restylane, Juvederm, and Perlane) and neurotoxin injectables (such as Botox and Dysport). Each has its own benefits and limitations factors that are determined primarily by the product's key active ingredient. Below is a chart for you to use as a general reference. For more detailed information about each of these products, click on the links in the list at left.

Of course, the best thing to do if you're considering a dermal filler or neurotoxin injectable treatment is to schedule a consultation with a knowledgeable physician. He or she will be able to advise you on which treatment will be safest and most effective for your particular skin and its needs.

Brand Name (Date of  FDA Approval) What It Treats Key Active Ingredient Length of Effectivenes Some Possible Side Effects
Dysport (2009)

 

Frown (glabellar) lines. Off-label: other dynamic facial wrinkles Botulinum toxin type A 3-6 months (perhaps longer) Bruising and numbness at injection site; headache; nose and throat irritation; in rare cases, droopy eyelids
Botox  (2002)   Frown (glabellar) lines and excessive sweating (hyperhidrosis). Off-label: other dynamic facial wrinkles Botulinum toxin type A 3-6 months for wrinkles; up to 1 year for hyperhidrosis Bruising, redness, and numbness at injection site; nausea and headache; in rare cases, droopy eyelids 
Zyderm & Zyplast (1981 & 1985) Frown (glabellar) lines; nasolabial folds; acne scars; other soft tissue defects. (Zyderm is used for superficial lines, while Zyplast is used for deeper wrinkles.)  Off-label: non-facial areas Purified bovine-derived (cow) collagen Zyderm: 2-5 months; Zyplast: 9-12 months Tenderness, redness, swelling and bruising at injection site
Cosmoderm & Cosmoplast (2003) Fine lines, wrinkles, and scars. (Cosmoderm is used for superficial lines, while Cosmoplast is used for deeper wrinkles.) Off-label: non-facial areas Purified human collagen 2 - 3 months Swelling and redness at injection site; in rare cases, small temporary bumps may form under skin
Autologous Fat Fillers  (doesn't require FDA approval) Deep wrinkles; lost  volume to cheeks, lips and other facial areas (as well as to the back of hands) Patient's own fat (removed from buttocks, abdomen, or  thighs) 3-12 months Tenderness, redness, and swelling at treated area and at area from which fat is removed
Radiesse (2006) Nasolabial folds. Off-label:  other facial wrinkles,  folds, and depressions Calcium hydroxylapatatite (CaHA) particles suspended in a carboxymethyl-cellulose gel About 1 year Swelling and bruising at injection site
Restylane (2003) Lines around the mouth and lips. Off-label: Lines around the eyes and elsewhere on the face; adding volume to lips, cheeks and other facial areas Hyaluronic acid Facial lines: 6-9 months; fuller lips: 3- 6 months Swelling, redness, and bruising at injection site; in rare cases, small temporary bumps may form under skin
Juvederm Ultra & Juvederm Ultra Plus (2001 & 2007) Moderate to deep wrinkles and creases around mouth Hyaluronic acid 4 -9 months Tenderness, swelling, bruising, redness, and itching around the  injection site; in rare cases, small temporary bumps may form under skin
Sculptra (2009 for cosmetic purposes; 2004 for lipoatrophy) Nasolabial folds and other deep facial wrinkles; facial fat loss(lipoatrophy),  including "hollow" cheeks, in people living with HIV/AIDS Poly-L-lactic acid Up to 2 years Swelling, redness, and bruising at injection site; in rare cases, small temporary bumps may form under skin
Perlane (2007) Nasolabial folds and other moderate to severe facial wrinkles Hyaluronic acid 3-6 months Swelling and redness at injection site; in rare cases, small temporary bumps may form under skin

 

Last modified: December 6, 2009
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 Excellent so far

I have never had anything done before - ever. As this is my ...[more]
Santa Barbara, CA Jul 03, 2010

 I switched.

I have been using Botox and decided to try dysport because o...[more]
Denver, CO Jun 12, 2010

 Great Dysport Experience

Dysport was a great decision, because it was something I wan...[more]
Plano, TX May 18, 2010
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Q: Are there any creams that to improve the skin?
Perhaps the best wrinkle fighter we have is sunscreen. The... [Read More]
Q: What is hyaluronic acid?
Hyaluronic acid is a natural sugar found throughout the... [Read More]
Q: What can Botox treat?
Botox is an outstanding drug, one that I have been injecting... [Read More]
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