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What causes wrinkles/aging
skin?

	Frown Lines
	Lip and Mouth wrinkles
	Eye wrinkles & Crow's Feet
	Neck

What are free radicals?

What is collagen?

What is elastin?

Does smoking cause wrinkles?

Does tanning cause wrinkles?

Laser Skin Rejuvenation

Laser Skin Resurfacing

	C02 Laser
	Erbium Laser

Plasma Skin Regeneration

Portrait® Plasma

Fractional Laser Resurfacing

	Fraxel®
	Affirm™

Radiofrequency Rejuvenation

	Thermage®
	Aluma™

Intense Pulsed Light (IPL)

Injectables & Dermal Fillers

	Artefill®
	Botox®
	Collagen
	CosmoDerm® & CosmoPlast®
	Fat Fillers
	Radiesse®
	Restylane®
	Sculptra®
	Juvederm®
	Perlane™

Medical & Topical Treatments

Microdermabrasion

Chemical Peel

How much does it cost?

Treatment comparison chart

Which wrinkle treatment is for
ME?

Pre-treatment Questions

Preventing Wrinkles

American Academy of Dermatology

American Society for Laser Medicine and Surgery

American Society for
Dermatologic Surgery

AAFPRS

Collagen Injections

What is Zyderm & Zyplast Collagen?

One method of repairing the appearance of our skin is by injecting purified bovine collagen directly into our skin. Collagen is a main protein in our skin, and as we age our collagen is damaged by the sun and begins to look less healthy and youthful. Collagen can be used to fill in deeper wrinkles, fine lines, as well as scars such as acne scarring.

Injectable collagen was patented by the Collagen Corporation under the trade names Zyderm^® and Zyplast^® and received FDA approval in 1981.

Zyderm I is a formula of 25% bovine collagen, 0.3% lidocaine. It is typically used for more superficial fines lines and wrinkles. Zyderm II is 50% bovine collagen, 0.3% lidocaine, and is generally used on more moderate scarring and wrinkles. Zyplast is used on the more severe wrinkling and scarring, and has a more dense composition.

How Long Do they Last?

Zyplast I is said to last anywhere from 6 weeks to 3 months.

Zyplast II may last 4 to 5 months.

Zyderm can last 9 months to 1 year.

During the Treatment

Before receiving collagen injections your physician should do a test patch on your skin to see if you are allergic to the substances that make up the collagen injections. If your doctor determines that you are not allergic, treatment will begin. Treatment with collagen consists of your doctor using a fine needle and inserting the injections at several different points along the treatment area. Generally a patient may feel a slight stinging or burning sensation during the treatment session.

Cost of Collagen Injections

The cost per treatment session can run anywhere from $350 to $500 per cc injected.

Post-Treatment

Immediately after the injections are administered there may be some discomfort, stinging or pain around the treatment area. In some cases bruising may also follow, but is usually minor. This should pass within a few days and any associated swelling will also pass. If you notice the symptoms after several days, it is advisable to contact your doctor.

Results from Collagen

Typically fine lines and wrinkles will be noticeably smaller and less defined after treatment. The length of time the treatments are effective depends on your individual case and should be discussed with your doctor. Generally patients see effective results for two to three months.

Alternative injectables for treating wrinkles include: Artefill, Botox, Radiesse, Restylane, Sculptra, Juvederm, Fat Fillers, CosmoDerm & CosmoPlast and Perlane.

Or, Which Treatment is Right for Me?

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Last Modified: Febuary 20, 2008

Frequently Asked Questions
	What is Adipose?	What is the Dermis?
	What is the Collagen and Elastin Matrix?	What is the Epidermis?
	What is Solar Elastosis?	What is Plasma Skin Regeneration?
	What are the five signs of sun-aged skin?	What is Hyaluronic Acid?
	What is Collagen?	What is the nasolabial fold?
	What is a GAG (Glycosaminoglycans)?	What is poly-L-lactic acid?
	What are Anti-Oxidents?	What is lidocaine?
	What is Skin Laxity?	What are granulomas?
	What are Retinoids?	What is neocollagenesis?
	What is the Stratum Corneum?	What is hypopigmentation?
	What is Ultraviolet Light?	What is hyperpigmentation?
	What is photo-damage?

The information contained in the above article is purely for educational purposes and is not intended to provide any medical advice. Always consult with your physician before having any medical procedure performed.